Creatine After 40? The Study Showing Big Brain Benefits for Women

You’ve probably heard creatine is for gym gains, but a brand-new clinical trial just proved that it does something far more powerful. In this video, I break down the 2025 Journal of the American Nutrition Association study showing that just 750 milligrams of creatine HCl, not 10 or 20 grams, can significantly increase brain creatine in women over 40.

No bloating. No water retention. Just measurable improvements in focus, reaction time, mood, and mental energy, along with better lipid markers and signs of healthier brain aging.

Here’s what I cover in this video:

• Why the female brain becomes energy-starved after 40 as estrogen declines

• How creatine fuels neurons by recycling ATP, the brain’s energy currency

• The difference between creatine HCl and monohydrate, and why the older formulas caused bloating

• The latest evidence for creatine’s role in mental clarity, mood stability, and metabolic health

• How to use it daily to support both brain and muscle energy

If you’re noticing brain fog, fatigue, or slower recovery, this is for you. Creatine HCl may be one of the most important longevity tools for women after 40. I’ll walk you through the research, how to use it safely, and what I’ve noticed in my own routine.